Potential answers for "'___ my wit's end!'"

⭐⭐⭐⭐ IAMAT
⭐⭐⭐ IMAT
⭐⭐⭐ ERMA
⭐⭐⭐ AMAT
⭐⭐⭐ PUN
⭐⭐⭐ BOMBECK
⭐⭐⭐ ERMABOMBECK
⭐⭐⭐ NESS
⭐⭐⭐ QUIP

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Follower of sigma   Stranded genetic stuff   Ill-suited