Potential answers for "Cause a dire problem"

⭐⭐⭐⭐ POSEAREALTHREAT
⭐⭐ ECOLI
⭐⭐ AWFUL
⭐⭐ ACUTE
⭐⭐ SEVERE
⭐⭐ GRIEVOUS
⭐⭐ DREADFUL
⭐⭐ TRAGIC
⭐⭐ ISITME
⭐⭐ GRIM

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