Potential answers for "Challenging, informally"

⭐⭐⭐⭐ GNARLY
⭐ MOUSERS
⭐ STOLI
⭐ MEDS
⭐ FASTONE
⭐ HITUP
⭐ COMBO
⭐ FLIX
⭐ DETOX
⭐ THEGIPPER

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Crossed off   Small thing to keep on track   Making level