Potential answers for "Difficulty, informally"

⭐⭐⭐⭐ PROB
⭐ MOUSERS
⭐ STOLI
⭐ MEDS
⭐ FASTONE
⭐ HITUP
⭐ COMBO
⭐ FLIX
⭐ DETOX
⭐ LUG

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