Potential answers for "Drug that's a downer"

⭐⭐⭐⭐ OPIATE
⭐⭐⭐ TRANK
⭐⭐ SPEEDBUMP
⭐⭐ ROOFIE
⭐⭐ LSD
⭐⭐ DRAG
⭐⭐ ABM
⭐⭐ XANAX
⭐⭐ ANODYNE
⭐⭐ ACE

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