Potential answers for "Make extremely upset"

⭐⭐⭐⭐ GUT
⭐⭐⭐ MAD
⭐⭐⭐ INARMS
⭐⭐⭐ HASKITTENS
⭐⭐⭐ IRATE
⭐⭐ IRK
⭐⭐ PARCH
⭐⭐ THROWINTOAPANIC
⭐⭐ RILE
⭐⭐ SORELOSERS

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"Sure, it could be"   Subj. of the 17th Amendment   Rafter neighbor