Potential answers for "Not born yesterday, so to speak"

⭐⭐⭐⭐ ASTUTE
⭐⭐⭐ KANIN
⭐⭐⭐ WASNT
⭐⭐⭐ NAIVE
⭐⭐⭐ NEONATAL
⭐⭐⭐ OHSURE

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Pill alternatives, in brief   C.D., e.g.: Abbr.   Apt name for a thief