Potential answers for "One of the giants of science"

⭐⭐⭐⭐ NEWTON
⭐⭐⭐⭐ ISAACNEWTON
⭐⭐⭐ ISAAC
⭐⭐ GENRE
⭐⭐ GREATDANE
⭐⭐ TITANS
⭐ PLEADER
⭐ MOE
⭐ ACHENE
⭐ ANDY

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Middle of the second century   Spiritual exercise   Admired exemplar