Potential answers for "Region of ancient Mesopotamia "

⭐⭐⭐⭐ SUMER
⭐⭐⭐ EDESSA
⭐⭐⭐ ZIGGURAT
⭐⭐⭐ IRAQ
⭐⭐⭐ ASSYRIA
⭐⭐ AEOLIS
⭐⭐ IONIA

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Expresses disapproval, in a way   Shrank (from)   Go out on a limb