Potential answers for "Significant effect"

⭐⭐⭐⭐ IMPACT
⭐⭐⭐ IMPACTFUL
⭐⭐ NAUSEA
⭐ EPOCHAL
⭐ IDLES
⭐ SETIN
⭐ ENACT
⭐ ADOPT
⭐ MAINSQUEEZE

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