Potential answers for "Source of great trouble"

⭐⭐⭐⭐ SCOURGE
⭐⭐ ENOS
⭐⭐ GOLCONDA
⭐⭐ CANOFWORMS
⭐⭐ PANDORASBOX
⭐⭐ BISON
⭐⭐ YANKEEINGENUITY
⭐⭐ MYSTICSHRIVER
⭐⭐ HORNETSNEST
⭐⭐ COMEDYGOLD

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