DAMPS
DAMPs
Damage-associated molecular pattern molecules also known as danger-associated molecular pattern molecules, are molecules that can initiate and perpetuate immune response in the noninfectious inflammatory response. Many DAMPs are nuclear or cytosolic proteins. When released outside the cell or exposed on the surface of the cell following tissue injury, they move from a reducing to an oxidizing milieu, which results in their denaturation. Also, following necrosis, tumor DNA is released outside the nucleus, and outside the cell, and becomes a DAMP.The above text is a snippet from Wikipedia: DAMPs
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