ENDONUCLEASE

Endonuclease

Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain. There is a small number of significant classes of endonucleases that cleave only at the specific nucleotide sequences . At the extreme ends of a sequence there are restriction endonucleases, usually called restriction enzymes. These are endonucleases from eubacteria and archea that recognize a specific DNA sequence. The nucleotide sequence recognized for cleavage by a restriction enzyme is called the restriction site. Typically, a restriction site will be a palindromic sequence of about four to six nucleotides long. Most restriction endonucleases cleave the DNA strand ...

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endonuclease

Noun

  1. Any enzyme which catalyzes the cleavage of nucleic acids so as to produce variously sized fragments.


The above text is a snippet from Wiktionary: endonuclease
and as such is available under the Creative Commons Attribution/Share-Alike License.

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