METHEMOGLOBINEMIA

Methemoglobinemia

Methemoglobinemia is a disorder characterized by the presence of a higher than normal level of methemoglobin in the blood. Methemoglobin is a form of hemoglobin that contains ferric 3+'>3 iron and has a decreased ability to bind oxygen. However, the ferric iron has an increased affinity for bound oxygen. The binding of oxygen to methemoglobin results in an increased affinity of oxygen to the three other heme sites within the same tetrameric hemoglobin unit. This leads to an overall reduced ability of the red blood cell to release oxygen to tissues, with the associated oxygen–hemoglobin dissociation curve therefore shifted to the left. When methemoglobin ...

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methemoglobinemia

Noun

  1. A form of toxic anemia characterized by the presence of methemoglobin in the blood


The above text is a snippet from Wiktionary: methemoglobinemia
and as such is available under the Creative Commons Attribution/Share-Alike License.

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