Potential answers for "Render purer"

⭐⭐⭐⭐ REFINE
⭐⭐ REFILTER
⭐ DROWN
⭐ TAINT
⭐ DEVELOP
⭐ THEHEARTOUTOF
⭐ ERASE
⭐ VOID
⭐ DEFUSE
⭐ OBVIATE

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Dominant one   Prefix from the Greek for "house"   Retin-A target