SULFATION

Sulfation

Sulfation in biochemistry is the enzyme-catalyzed addition of sulfate to another molecule. It often refers to a phase II enzyme reaction. This biotransformation process uses its cosubstrate 3'-phosphoadenosine-5'-phosphosulfate to transfer sulfate to a xenobiotic. Most of the time this is effective in rendering the xenobiotic less active from a pharmacological and toxicological standpoint, but sometimes it plays a role in the activation of xenobiotics .

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sulfation

Noun

  1. The replacement of a hydrogen atom of an organic compound with a sulfate (-OSO2OH) functional group, or the replacement of the hydrogen atoms of two molecules to form a sulfate (R-OSO2O-R)


The above text is a snippet from Wiktionary: sulfation
and as such is available under the Creative Commons Attribution/Share-Alike License.

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